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Are your patients’ abilities going up in smoke?

Even if you can’t see smoldering neuroinflammation, you can hear it in patients’ stories. Watch the videos to see how it may have impacted the lives of 3 people living with MS, across the spectrum of disease.
 

Choose a patient story

Inspired by real patients

Image of an MS patient called Albert. Inspired by a real patient

Albert, RRMS

“I’m worried about being able to take care of my family.”

Watch his story
Image of an MS patient called Sonia. Inspired by a real patient

Sonia, RRMS

“My friends always call me a dreamer, but they don’t know how I really feel.”

Watch her story
Image of an MS patient called Marissa. Inspired by a real patient

Marissa, SPMS

“Everything felt harder to do—even the things I used to love doing.”

Watch her story


Albert, age 36, diagnosed with RRMS

Inspired by a real patient

  • Time since diagnosis: 9 years
  • Started on treatment at diagnosis
  • Time since last relapse/MRI change: 7 years
  • Disability level: Moderate
  • Experiencing difficulty with:
    • Mobility
    • Fatigue
    • Gait
Illustration of a brain scan

Diagnosis:

  • Diagnosed with RRMS at 27 years old
  • Lesions per MRI and clinical relapse with left leg weakness
  • Started on high-efficacy DMT
Illustration of person with a difficult gait

Year 4:

  • Changes to fatigue, balance, and cognition
  • Decline starting to impact social activities and sports
  • Stable MRI and EDSS with no relapses
Illustration of a person looking fatigued

Year 6:

  • Stable EDSS
  • Work performance concerns
  • Changes in cognitive testing (SDMT)
  • Weakness and spasticity noted on lower extremity exam
Illustration of a walker

Year 9:

  • No clinical relapses or new MRI lesions
  • More frequent tripping episodes
  • Changes to EDSS and SDMT
  • Concerns with ability to continue working

 


Sonia, age 35, diagnosed with RRMS

Inspired by a real patient

  • Time since diagnosis: 3 years
  • Started on treatment at diagnosis
  • Time since last relapse/MRI change: 2 years
  • Disability level: Mild
  • Experiencing difficulty with:
    • Cognition
    • Endurance
    • Mobility
Illustration of a brain scan

Diagnosis:

  • Diagnosed with RRMS at 32 years old
  • MRI with lesions and clinical relapse of dizziness and imbalance
  • Started on high-efficacy DMT
illustration of a brain with a puzzle piece

Year 2:

  • Stable MRI, no clinical relapses
  • Brain fog and early cognitive changes
  • Stable EDSS
Illustration of a face smiling and another face frowning

Year 3:

  • Stable MRI and EDSS
  • Increased fatigue and mood changes
  • Reduced participation in social activities and work
     

 


Marissa, age 45, diagnosed with SPMS

Inspired by a real patient

  • Time since diagnosis: 10 years
  • Started on treatment at diagnosis
  • Time since last relapse/MRI change: 8 years
  • Disability level: Moderate
  • Experiencing difficulty with:
    • Memory
    • Processing speed
    • Endurance
Illustration of a brain scan

Diagnosis:

  • Diagnosed with RRMS at 35 years old
  • Lesions per MRI and clinical relapse with optic neuritis
  • Started on high-efficacy DMT
Illustration of a foot on an incline

Year 3:

  • Stable MRI, no clinical relapses
  • Early cognitive changes affecting work performance
  • Stable EDSS
  • Changes to balance and stamina impacting running ability (decreased from 10K to 5K)
Illustration of a brain and speed monitor superimposed on eachother

Year 7:

  • Decline in writing ability; finding it difficult to work
  • Bladder control issues
  • Changes to balance, gait, and endurance
  • Changes to EDSS and SDMT
Illustration of the text "SPMS" in a circle

Year 10:

  • Diagnosed with SPMS at 45 years old
  • Filed for employment support

 

Illustration of a smoldering brain and a magnifying glass showing microglia in the brain

Which gradual signs or symptoms of smoldering neuroinflammation have you seen in your patients?

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Resources

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